Intra-cytoplasmic Morphologically Selected Sperm Injection (IMSI) is a real-time method where sperms are selected before the microinjection takes place. This is done using an inverted microscope that is able to provide a much greater magnifying power (around 6,600 times) than those that are normally used in reproductive laboratories (400 times) to carry out the ICSI.

Standard ICSI (approximately 200x magnification)

IMSI ( approximately 6000x magnification)

The advantage of IMSI


  • To choose good quality sperm
  • Improve fertilization and normal embryo development
  • Reduce miscarriage rate
  • Increase pregnancy rate


Who is IMSI for?


This is a treatment option if the male has

  • poor sperm motility
  • poor sperm morphology
  • a low sperm count
  • surgically recovered sperm